| Doxycycline-dependent Cas9-expressing pig resources for conditional in vivo gene nullification and activation |
Jin, Qin; Liu, Xiaoyi; Zhuang, Zhenpeng; Huang, Jiayuan; Gou, Shixue; Shi, Hui; Zhao, Yu; Ouyang, Zhen; Liu, Zhaoming; Li, Lei; Mao, Junjie; Ge, Weikai; Chen, Fangbing; Yu, Manya; Guan, Yezhi; Ye, Yinghua; Tang, Chengcheng; Huang, Ren; Wang, Kepin; Lai, Liangxue |
2023 |
GENOME BIOLOGY |
| Prolonged generation of multi-lineage blood cells in wild type animals from pluripotent stem cells |
Huan Peng , Yunqing Lin , Fangxiao Hu , Cui Lv , Bingyan Wu , Qitong Weng , Lijuan Liu , Chengxiang Xia , Xiaofei Liu , Yalan Zhao , Qi Zhang , Yang Geng , Mengyun Zhang , Jinyong Wang |
2023 |
Stem Cell Reports |
| Design, Synthesis, and Biological Evaluation of 1-(Indolizin-3-yl)ethan-1-ones as CBP Bromodomain Inhibitors for the Treatment of Prostate Cancer |
Qiuping Xiang, Chao Wang, Tianbang Wu, Cheng Zhang, Qingqing Hu, Guolong Luo, Jiankang Hu , Xiaoxi Zhuang, Lingjiao Zou , Hui Shen, Xishan Wu , Yan Zhang , Xiangqian Kong, Jinsong Liu, Yong Xu |
2022 |
Journal of Medicinal Chemistry |
| Shared IGHV1-69-encoded neutralizing antibodies contribute to the emergence of L452R substitution in SARS-CoV-2 variants |
Qihong Yan , Ruitian Hou , Xiaohan Huang , Yanjun Zhang , Ping He , Yudi Zhang , Banghui Liu , Qian Wang , Haiyue Rao , Xianying Chen , Xinwei Zhao , Xuefeng Niu , Jincun Zhao , Xiaoli Xiong , Ling Chen |
2022 |
Emerging Microbes & Infections |
| Origin and Reversion of Omicron Core Mutations in the Evolution of SARS-CoV-2 Genomes |
Xin-Wei Zhao, Luyao Qin, Xiao Ding, Yudi Zhang, Xuefeng Niu, Feng Gao , Taijiao Jiang
and Ling Chen. |
2022 |
Viruses |
| Discovery, optimization and evaluation of 1-(indolin-1-yl)ethan-1- ones as novel selective TRIM24/BRPF1 bromodomain inhibitors |
Qiuping Xiang,Guolong Luo,Cheng Zhang,Qingqing Hua,Chao Wang,Tianbang Wu,c,Hongrui Xu,Jiankan gHu,Xiaoxi Zhuang,Maofeng Zhang,Shuang Wu,Jinxin Xu,YanZhang,Jinsong Liu,Yong Xu |
2022 |
European Journal of Medicinal Chemistry |
| Nuclear localization of mitochondrial TCA cycle enzymes modulates pluripotency via histone acetylation |
Wei Li, Qi Long , Hao Wu, Yanshuang Zhou , Lifan Duan, Hao Yuan , Yingzhe Ding , Yile Huang , Yi Wu , Jinyu Huang, Delong Liu, Baodan Chen, Jian Zhang , Juntao Qi, Shiwei Du, Linpeng Li , Yang Liu, Zifeng Ruan, Zihuang Liu, Zichao Liu, Yifan Zhao , Jianghuan Lu, Junwei Wang, Wai-Yee Chan & Xingguo Liu. |
2022 |
Nature Communications |
| Integrative analysis reveals structural basis for transcription activation of Nurr1 and Nurr1-RXRα heterodimer |
Mohan Zhao,Na Wang,Yaoting Guo,Jingwen Li,Yue Yin,Yan Dong,Jiabin Zhu,Chao Peng,Tingting Xu,Jinsong Liu |
2022 |
Proceedings of the National Academy of Sciences of the United States of America |
| YY1 safeguard multidimensional epigenetic landscape associated with extended pluripotency |
Xiaotao Dong,？Rong Guo,？Tianrong Ji,？Jie Zhang,？Jun Xu,？Yaoyi Li,？Yingliang Sheng,？Yuxiang Wang,？Ke Fang,？Yulin Wen,？Bei Liu,？Gongcheng Hu,？Hongkui Deng,？Hongjie Yao |
2022 |
Nucleic Acids Research |
| Identification of a group of bisbenzylisoquinoline (BBIQ) compounds as ferroptosis inhibitors |
Yipu Fan, Yihan Zhang, Kunyu Shi, Shan Cheng, Duanqing Pei and Xiaodong Shu |
2022 |
Cell Death＆Disease |
| From immune equilibrium to immunodynamics |
Xiaoping Chen |
2022 |
Frontiers in Microbiology |
| Parallel Kinetic Resolution through Palladium-Catalyzed Enantioselective Cycloimidoylation: En Route to Divergent N-Heterocycles Bearing a Quaternary Stereogenic Center |
Xilong Wang, Yu Luo, Jing Li, Chaoqin Wang, Qianwen Liu, Yimiao He, Shuang Luo* and Qiang Zhu |
2022 |
ACS Catalysis |
| Hepatic DKK1-driven steatosis is CD36 dependent |
Zhen Yang？,？Xinping Huang,？Jiaye Zhang,？Kai You,？Yue Xiong,？Ji Fang,？Anteneh Getachew,？Ziqi Cheng,？Xiaorui Yu,？Yan Wang,？Feima Wu,？Ning Wang,？Shufen Feng,？Xianhua Lin,？Fan Yang,？Yan Chen,？Hongcheng Wei,？Yin-Xiong Li |
2022 |
LIFE SCIENCE ALLIANCE |
| Harnessing enhanced CRISPR/Cas12a trans-cleavage activity with
extended reporters and reductants for early diagnosis of Helicobacter pylori,
the causative agent of peptic ulcers and stomach cancer |
Jean de Dieu Habimana, Omar Mukama, Guiquan Chen, Mengjun Chen, Obed
Boadi Amissah, Lin Wang, Yujie Liu, Yirong Sun, Amy L. Li, Sihao Deng,
Jufang Huang, Xiao-xin Yan, Theobard Rutaganda, Dieudonne Mutangana, Lin-Ping Wu,
Rongqi Huang ,Zhiyuan Li |
2022 |
Biosensors and Bioelectronics |
| IReNA: integrated regulatory network analysis of single-cell transcriptomes and chromatin accessibility profiles |
Junyao Jiang,Pin Lyu,Jinlian Li,Sunan Huang,Jiawang Tao,Seth Blackshaw,Jiang Qian,and Jie Wang. |
2022 |
iScience |
| Structural Studies Reveal Unique Non-canonical Regulators of G Protein Signaling Homology (RH) Domains in Sorting Nexins |
Yulong Zhang,Rui Chen,Yan Dong,Jiabin Zhu, Kai Su,Jinsong Liu and Jinxin Xu |
2022 |
JOURNAL OF MOLECULAR BIOLOGY |
| Preclinical Study of Plasmodium Immunotherapy Combined with Radiotherapy for Solid Tumors |
Tao, Zhu, Wenting Ding, Zhipeng Cheng, Yinfang Feng, Zhongkui Kang, Runmin Qiu, Siting Zhao, Wen Hu, Fang Zhou, Donghai Wu, Ziyuan Duan, Li Qin, and Xiaoping Chen. |
2022 |
Cells |
| Shared IGHV1-69-encoded neutralizing antibodies contribute to the emergence of L452R substitution in SARS-CoV-2 variants |
Qihong Yan, Ruitian Hou, Xiaohan Huang, Yanjun Zhang, Ping He, Yudi Zhang, Banghui Liu, Qian Wang, Haiyue Rao, Xianying Chen, Xinwei Zhao, Xuefeng Niu, Jincun Zhao, Xiaoli Xiong, Ling Chen |
2022 |
Emerging Microbes & Infections |
| Multiplexed base editing through Cas12a variant-mediated cytosine and adenine base editors |
Fangbing Chen,Meng Lian,Bingxiu Ma,Shixue Gou,Xian Luo,Kaiming Yang,Hui Shi,Jingke Xie,Weika Ge,Zhen Ouyang,Chengdan Lai,Nan Li,Quanjun Zhang,Qin Jin,Yanhui Liang,Tao Chen,Jiaowei Wang,Xiaozhu Zhao,Lei Li,Manya Yu,Yinghua Ye,Kepin Wang,Han Wu& Liangxue Lai |
2022 |
Communications Biology |
| Double knock-in pig models with elements of binary Tet-On and phiC31 integrase systems for controllable and switchable gene expression |
Qin Jin,Xiaoyu Yang,Shixue Gou,Xiaoyi Liu,Zhenpeng Zhuang,Yanhui Liang, Hui Shi,Jiayuan Huang,Han Wu,Yu Zhao,Zhen Ouyang,Quanjun Zhang,Zhaoming Liu, Fangbing Chen,Weikai Ge, Jingke Xie,Nan Li,Chengdan Lai,Xiaozhu Zhao, Jiaowei Wang,Meng Lia,Lei Li,Longquan Quan, Yinghua Ye, Liangxue Lai,Kepin Wang |
2022 |
SCIENCE CHINA-Life Sciences |
| Substrate-induced dimerization of elaiophylin glycosyltransferase reveals a novel self-activating form of glycosyltransferase for symmetric glycosylation
glycosyltransferase reveals a novel self-activating form of
glycosyltransferase for symmetric glycosylation |
Tingting Xu, Qingqing Gan, Qiang Liu, Ruidong Chen, Xuhui Zhen,Changsheng Zhang and Jinsong Liu |
2022 |
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY |
| Booster vaccination is required to elicit and maintain COVID-19 vaccine-induced immunity in SIV-infected macaques |
Pingchao Li, Qian Wang, Yizi He, Chenchen Yang, Zhengyuan Zhang, Zijian Liu, Bo Liu, Li Yin, Yilan Cui, Peiyu Hu, Yichu Liu, Pingqian Zheng, Wei Wang, Linbing Qu, Caijun Sun, Suhua Guan, Liqiang Feng, Ling Chen |
2022 |
Emerging Microbes & Infections |
| Co-expression of a PD-L1-specific chimeric switch receptor augments the efficacy and persistence of CAR T cells via the CD70-CD27 axis |
Le Qin, Yuanbin Cui, Tingjie Yuan, Dongmei Chen, Ruocong Zhao, Shanglin Li, Zhiwu Jiang, Qiting Wu, Youguo Long, Suna Wang, Zhaoyang Tang, Huixia Pan, Xiaoping Li, Wei Wei, Jie Yang, Xuequn Luo, Zhenfeng Zhang, Qiannan Tang, Pentao Liu, Robert Weinkove , Yao Yao, Dajiang Qin, Jean Paul Thiery, Peng Li |
2022 |
Nature Communications |
| Palladium-Catalyzed Modular Synthesis of Enantioenriched Pyridohelicenes through Double Imidoylative Cyclization |
Ting Yu, Zhong-Qiu Li, Jing Li, Sidi Cheng, Jiali Xu, Jun Huang, Yu-Wu Zhong*, Shuang Luo* and Qiang Zhu* |
2022 |
ACS Catalysis |
| SARS-CoV-2 Delta and Omicron variants evade population antibody response by mutations in a single spike epitope |
Ping He, Banghui Liu, Xijie Gao, Qihong Yan, Rongjuan Pei, Jing Sun, Qiuluan Chen, Ruitian Hou, Zimu Li, Yanjun Zhang, Jincun Zhao, Hao Sun, Bo Feng, Qian Wang, Haisu Yi, Peiyu Hu, Pingchao Li, Yudi Zhang, Zhilong Chen, Xuefeng Niu, Xiaolin Zhong, Liang Jin, Xiaofeng Liu, Kun Qu, Katarzyna A. Ciazynska, Andrew P. Carter, John A. G. Briggs, Jizheng Chen, Jinsong Liu, Xinwen Chen, Jun He, Ling Chen and Xiaoli Xiong. |
2022 |
Nature Microbiology |
| Generation of a genetically modified pig model with CREBRF R457Q variant |
Yingying Li,Hai Wang,Huangyao Chen,Yuan Liao,Shixue Gou,Quanmei Yan,Zhenpeng Zhuang,Hao Li,Jiaowei Wang,Yangyang Suo,Ting Lan,Yang Liu,Yu Zhao,Qingjian Zou,Tao Nie,Xiaoyan Hui,Liangxue Lai,Donghai Wu,Nana Fan |
2022 |
FASEB Journal |
| Ectopic expression of meiotic cohesin generates chromosomeinstability in cancer cell line |
Abdelhalim Boukaba, Jian Liu, Carl Ward, Qiongfang Wu, Alexei Arnaoutov, Jierong Liang, Elena M Pugacheva, Mary Dasso, Victor Lobanenkov, Miguel Esteban, Alexander V Strunnikov |
2022 |
Proceedings of the National Academy of Sciences of the United States of America |
| Antipsychotic drugs induce vascular defects in hematopoietic organs |
Deng Zhao-Hua, Zhong Jing, Jiang Hai-Lin, Jeong Hyun-Woo, Chen Jian-Wei, Shu Ya-Hai, Tan Ming, Adams Ralf H, Xie Ke-Ping, Chen Qi, Liu Yang. |
2022 |
FASEB Journal |
| Massive Loss of Transcription Factors Promotes the Initial Diversification of Placental Mammals |
Xin-Wei Zhao, Jiaqi Wu, Hirohisa Kishino,Ling Chen. |
2022 |
International Journal of Molecular Sciences |
| COVID-19-associated liver injury: Clinical characteristics, pathophysiological mechanisms and treatment management. |
Penghui Li, Ying Liu, Ziqi Cheng, Xiaorui Yu, Yinxiong Li |
2022 |
Biomed Pharmacother |
